磁共振弥散加权成像在颅内感染病变的应用

Clinical Application of Diffusion-weighted MRI of Encephalic Infectious Disease

目的:探讨MRI弥散加权成像(Diffusion-Weighted Imaging)高信号在颅内感染性疾病的应用价值。方法:收集我院2004年9月至2007年6月经病理证实或临床治疗随访的颅内感染病例10例。在常规MRI基础上,加单次激发(SE-EPI)扩散加权序列(DWI),层厚、间距与常规扫描一致;在病灶区、对应正常区域分别进行ADC值测量。结果:10例感染病灶中8例DWI高信号,ADC值下降;2例病程较长,DWI呈等或低信号时,ADC值上升。结论:MRI弥散加权成像在颅内感染性疾病的鉴别诊断中起着重要作用。

Objective To assess clinical applications of using diffusion-weighted imaging （DWI） in encephalic infection diseases. Methods 10 patients with eneephalie infection diseases were investigated from September 2004 to June 2007. All patients underwent routine MRI and single-shoot DWI in which the thickness and space of routine MRI agreed with DWI. The ADC values at infection focus and opposite normal region were measured. Result Among the 10 cases, seven of them showed decreased ADC value when DWI presented hyper-intensity; whereas the other three, whose chronic infection were long-term, had increased ADC value while DWI presented iso-/hypo-intensity. Conclusion MRI diffusion-weighted imaging plays an important role in the diagnosis of encephalic infection diseases.