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Alzheimer病与血管性痴呆认知及精神行为症状的比较 被引量:3

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摘要 目的比较Alzheimer病(AD)与血管性痴呆(VaD)的认知障碍及精神行为症状(Psychological and behavioral symptoms of dementia,BPSD)特点。方法通过详细收集临床资料,对符合入组条件的29例AD与35例VaD患者采用简易精神状态检查量表(MMSE)和AD病理行为评分量表(BEHAVE-AD)进行比较分析。结果AD组认知功能损害程度最重,范围最广,AD组仅在图形描画稍优于VaD组,在时间定向、短程记忆、注意和计算、阅读理解显著低于VaD组;两组间在情感障碍、幻觉、焦虑和恐惧的发生率与严重程度上无显差异,VaD组行为紊乱、偏执与妄想观念的发生率显著低于AD组,严重程度却高于AD组,VaD组日夜节律紊乱、攻击行为的发生率及严重程度上均高于AD组,均有显著性差异。结论AD与VaD患者的认知功能障碍及BPSD可有不同特点,这对痴呆的诊断与鉴别诊断均具有重要参考价值。
出处 《齐齐哈尔医学院学报》 2008年第17期2070-2071,共2页 Journal of Qiqihar Medical University
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