臭氧联合射频治疗椎间盘突出的临床对比研究

EFFECTS OF OZONE CHEMONUCLEOLYSIS COMBINED WITH RADIOFREQUENCY HEATING ON LUMBAR DISC HERNIATION

目的:评价臭氧联合射频热凝对腰椎间盘突出症的疗效。方法:60例病人,随机分为臭氧化学溶核组(A组)和臭氧联合射频组(B组)。A组:分别于盘内和侧隐窝注射臭氧。B组:臭氧注射同A组,加突出物射频热凝。结果:术后3天、2周、2月腰痛和腿痛评分、Oswestry评分B组均明显低于A组(P<0.05或P<0.01)。亚组腿痛评分比较,术后3天、2周,B1组(8.9±4.4、7.8±4.9)和B2组(10.0±5.2、9.2±2.9)均明显低于A2组(16.9±7.9、13.8±4.7),P<0.01或P<0.05。结论:臭氧联合突出物射频治疗效果较单纯使用臭氧好,对非包容性椎间盘突出亦如此。

Objective： To assess the therapeutic outcome of combined ozone chemonucleolysis and radio- frequency heating on lumbar disc herniation. Methods： 60 patients were randomized to Ozone chemonucleolysis alone （group A） or combined with radiofrequeney heating management （group B）. Group A： received an intradiscal and lateral recess injection of an oxygen-ozone mixture. Group B： received, the radiofrequency heating targeting of the herniated disk material additionally. Results ： At 3 days, 2 weeks, 2 months after treatment, there were statistically significant differences between the groups A and B for leg pain scale （15.3 ±7.3, 12.8 ±4.3, 8.6 ±4.3 VS 6.2 ±3.9, 5.0 ±3.9, 4.5 ±3.8, P 〈0.01） ; back pain scale （26.7 ±9.6, 15.7±6.3, 11.2±5.0 VS 16.3 ±5.6, 8.8±8.6, 8.0 ±5.2, P〈0. 01） ;Oswestry disability scale at 2 weeks and 2 months （18.6 ±6.7 , 13.5 ±6.1 VS 13.2 ±6.6, 10.2 ±6.1, P〈0.01, P〈0.05）. At3 days, 2weeks, leg pain scale in subgroupB,（8.9±4.4, 7.8 ±4. 9） and B2（10.0 ±5.2, 9.2 ±2.9） were lower than in subgroup A2（16.9 ±7.9, 13.8±4.7）, P〈0. 01, P 〈 0.05. Conclusion ： The effect of ozone therapy combined with radiofrequency heating is greater than that of ozone alone.