促红细胞生成素治疗早产儿贫血疗效观察

Curative Effects Observation on Hemopoietin in Treating Anemia of Prematurity

目的：研究促红细胞生成素治疗早产儿贫血。方法：将我院收治的早产儿33例，分为治疗组17例、对照组16例，两组早产儿于生后4天起，口服维生素E15mg／d，维生素C 0．2g／d，铁剂自生后7天起两组均添加元素铁6mg／（kg·d）计算，疗程6周；治疗组于生后7天开始用国产rhEPO 600IU／（kg·w）隔日一次，每周3次皮下注射，疗程6周。结果：早产儿贫血发生率，RBC、Hb、中RBC的改变，对贫血早产儿输血的影响，血清铁蛋白的比较均存在显著差异。结论；采用rhEPO治疗早产儿效果好、且经济，值得基层推广。

Objective： To explore the effect of hemopoietin in treating anemia of prematurity. Methods： Dividing 33 cases of premature in our hospital into 2 groups： treament group （17 cases） and control group （16 cases）. Treating the 2 groups with VE （15mg/d）, VC （0. 2g/d） since they are 4 days old and adding iron 6mg/ （kg· d） since they are 7 days old for 6 weeks; treating the treatment group with rhEP0600IU/ （kg· w） two days once and hypodermic injection 3 times a week after they are born for 7 days for 6 weeks. Results： There are significant differences on RBC, Hb and so on between the 2 groups. Conclusion： It is effective to treat prematures with rhEP0.