摘要
内脏脂肪组织增加已被公认是动脉粥样硬化性疾病和代谢综合征的一个重要危险因素,对内脏脂肪组织的鉴别和评价是至关重要的。心外膜脂肪是沉积在心脏周围真正的脂肪组织,特别是围绕在冠状动脉周围。心外膜脂肪组织可表达多种与动脉粥样硬化相关的细胞因子和蛋白,与冠状动脉粥样硬化的发展密切相关。因心外膜脂肪组织特殊的解剖位置和生理生化特性,故可将其作为一个新的冠心病预测标记和代谢综合征潜在的治疗靶点。
Epicardial adipose tissue is true visceral fat deposited around the heart, particularly around subepieardial coronary vessels. While little is known about the pathophysiologic and metabolic roles of epicardial fat. Epicardial adipose tissue expresses numerous genes for eytokines and proteins associated with atheroselerosis. Epicardial adipose tissue may serve as a new predictive marker of coronary heart disease and potential therapeutic target in the metabolic syndrome.
出处
《医学研究生学报》
CAS
2008年第9期1002-1005,1008,共5页
Journal of Medical Postgraduates
基金
南京军区"十五"重点课题基金资助项目(批准号:06Z38)
