摘要
目的根据OCT图像,探讨特发性黄斑裂孔的发病机制。方法观察特发性黄斑裂孔59例65只眼的OCT图像。Ⅰ期裂孔6例6只眼;II期裂孔22例24只眼,其中Ⅱ期裂孔的早期10例10只眼,Ⅱ期裂孔的晚期12例14只眼;Ⅲ期裂孔21例25只眼;Ⅳ期裂孔10例10只眼。结果Ⅰ期裂孔中有4/6可观察到黄斑前双凸型玻璃体后脱离对中心凹的牵拉。Ⅱ期裂孔的早期中有9/10可观察到黄斑前双凸型玻璃体后脱离对中心凹的牵拉;Ⅱ期的晚期中有10/14可观察到裂孔盖膜,这些盖膜中有8/10可观察到含有部分撕脱下来的视网膜神经组织。Ⅲ期裂孔中有16/25及Ⅳ期裂孔中有7/10可观察到内界膜增厚,反光增强,部分患眼还可观察到合并有视网膜前膜的形成。结论特发性黄斑裂孔Ⅰ期和Ⅱ期的主要发病机制是中心凹玻璃体前后方向的牵拉,而Ⅲ期和Ⅳ期的主要发病机制是内界膜的收缩。
Objective To investigate the pathogenesis of IMH,according to the image of OCT. Patients and. Methods 59 eases (65 eyes) oflMH were examined by OCT. Stage Ⅰ :6 cases (6 eyes). Stage Ⅱ : 22 cases (24 eyes), early stage Ⅱ : 10 cases ( 10 eyes), late stage Ⅱ: 12 cases ( 14 eyes). Stage Ⅲ : 21 cases (25 eyes). Stage Ⅳ : 10 eases ( 10 eyes). Results In stage Ⅰ , 4/6 was found the traction of biconvex posterior vitreous detachment at fovea. In early stage Ⅱ, 9/10 was found the traction of biconvex posterior vitreous detachment at fovea. In late stage Ⅱ, 10/14 was found the opereulum, and among the opercula, 8/10 was found some evulsed retinal tissue. In stage Ⅲ and Ⅳ, 16/25 and 7/10 were found that the thickness and glisten of internal limiting membrane (ILM) were increased, and epretina membrane could be found in some cases. Conelusion In stageⅠ and Ⅱ ,the pathogenesis of IMH is the fore-and-aft traction of vitreous at the fovea. In stage Ⅲ and Ⅳ,the pathogenesis of IMH is the contraction of ILM.
出处
《中国实用眼科杂志》
CSCD
北大核心
2008年第8期860-862,共3页
Chinese Journal of Practical Ophthalmology