摘要
Giant duodenal ulcers （GDUs） are a subset of duodenal ulcers that have historically resulted in greater morbidity than usual duodenal ulcers. Until recently, few cases had been successfully treated with medical therapy. However, the widespread use of endoscopy, the introduction of H-2 receptor blockers and proton p^Jmp inhibitors, and the improvement in surgical techniques all have revolutionized the diagnosis, treatment and outcome of this condition. Nevertheless, GDUs are still associated with high rates of morbidity, mortality and complications. Thus, surgical evaluation of a patient with a GDU should remain an integral part of patient care. These giant variants, while usually benign, can frequently harbor malignancy. A careful review of the literature highlights the important differences when comparing GDUs to classical peptic ulcers and why they must be thought of differently than their more common counterpart.
Giant duodenal ulcers (GDUs) are a subset of duoden ulcers that have historically resulted in greate morbidity than usual duodenal ulcers. Until recentl few cases had been successfully treated with medic therapy. However, the widespread use of endoscop the introduction of H-2 receptor blockers and proto pump inhibitors, and the improvement in surgic techniques all have revolutionized the diagnosi treatment and outcome of this condition. Nevertheles GDUs are still associated with high rates of morbidit mortality and complications. Thus, surgical evaluatio of a patient with a GDU should remain an integral pa of patient care. These giant variants, while usual benign, can frequently harbor malignancy. A caref review of the literature highlights the importan differences when comparing GDUs to classical pept ulcers and why they must be thought of different than their more common counterpart.
