非酒精性脂肪肝分子发病机制的研究进展

Advance in the molecular pathogenesis of nonalcoholic fatty liver disease

非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)是一种常见肝病,且发病率有逐年增加的趋势.本文概述近年来国内外学者在NAFLD发病机制方面的主要成果和观点,探讨在NAFLD发病中基因的作用,旨在阐明NAFLD发病的分子机制.

Nonalcoholic fatty liver disease （NAFLD） is a common liver disease and its incidence rate is increasing year by year. In this paper, we investigated and summarized the studies on the mechanisms of NAFLD in recent years, aiming at illustrating the roles of genes in NAFLD and their molecular mechanisms.