变应性鼻炎和鼻鼻窦炎与哮喘发病之间的关系

Interrelationship among allergic rhinitis,rhinosinusitis and asthma in pathogenesis

变应性鼻炎和鼻鼻窦炎常常与哮喘并发,其间的关系探讨已久。从流行病学角度看,三者存在高患病率的特征,且常常互相伴发并互为危险因素和提示不良预后。解剖生理存在解剖发育上的异同,参与疾病的形成。病理生理角度环境因素等介导"共同气道"的慢性炎症。其间由免疫机制等因素构成上下气道的连续性表现。文章从以上方面对变应性鼻炎、鼻鼻窦炎和哮喘发病之间的关系作一综述。

Allergic rhinitis and rhinosinusitis often complicate with asthma, and their relationship has long been investigated. From the view of epidemiology, all of these three diseases have higher prevalence, complicate with each other, are risk factors and prognostic factors for each other. Besides, they share common in anatomy and pathophysiology. In this paper, the interrelationship among allergic rhinitis, rhinosinusitis and asthma in pathogenesis is discussed.