极低频脉冲电磁场对小鼠免疫功能的影响

Effects of ELF pulsed EMF on immunological function in mice

目的:研究极低频脉冲电磁场对小鼠免疫功能的影响。方法:磁场强度为4高斯,频率为5Hz的极低频脉冲电磁场连续全身作用4周龄小鼠60天后,测定小鼠血清抗体(IgG、IgM、IgA)的含量、腹腔巨噬细胞吞噬功能、胸腺指数和脾脏指数。结果:磁场组的IgG、IgM含量、脾脏指数显著高于对照组(p<0.01);磁场组腹腔内巨噬细胞吞噬率显著高于对照组(p<0.05)。结论:磁场强度为4高斯,频率为5Hz的极低频脉冲电磁场对小鼠的免疫功能有增强作用。

Object： To investigate the effects of extremely low frequency（ELF） pulsed electromagnetic fields（EMF） on immunological function in mice. Methods： 4_week_old mice were whole_body exposed to ELF fields with frequency of 5Hz, intensity of 4 Gs for 60 days. The contents of serum immunoglobulin G（IgG）, IgM and IgA, the function of abdominal cavity macrophage, the thymus index and the spleen index were measured respectively. Results： The contents of IgG, IgM in serum, the spleen index in magnetic group were significantly higher than that of control（p〈0.0l）; A significant enhancement of phagocytosis rate was observed in magnetic group（p〈0.05）. Conclusions： ELF pulsed electromagnetic fields of 4Gs ,5Hz can reinforce immunological function in mice.