核素心室造影评价不同部位心肌梗死患者的左室整体和局部功能

Radionuclide ventriculography assessment of global and regional left ventricular function in the patients with myocardial infarction at different locations

目的应用放射性核素心室造影技术对不同部位的左室心肌梗死(MI)患者进行左室整体和局部收缩和舒张功能参数的对比分析。方法选择对照组15例、下壁MI组24例、前壁MI组29例,利用放射性核素心室造影技术评价3组的左室整体和局部的收缩与舒张功能参数。结果①左室整体收缩功能,在左室射血分数和峰射血率二个参数中,下壁MI组与对照组相比有显著下降(P<0.05),前壁MI组与对照组和下壁MI组相比,分别有显著下降(P<0.05)。②左室整体舒张功能,在峰充盈率和前1/3充盈分数二个参数中,前壁MI组与对照组和下壁MI组相比分别有显著下降(P<0.05)。③左室局部收缩功能,在以左室局部射血分数为参数时,下壁MI组在4个节段与对照组相比有显著下降(P<0.05),前壁MI组在4个节段与对照组相比有显著下降(P<0.05),前壁MI组在2个节段比下壁MI组有显著下降(P<0.05)。④左室局部舒张功能,在以LVR1/3FF为参数时,下壁MI组和前壁MI组分别与对照组相比在4个节段上有显著下降(P<0.05),前壁MI组在2个节段上比下壁MI组有显著下降(P<0.05)。结论前壁MI对左室整体和局部收缩与舒张功能的损害重于下壁MI。

AIM To compare and analyze global and regional ventricular systolic and diastolic functions by radionuclide ventriculography technique in patients with left ventricular myocardial infarction at different locations. METHODS We selected control group （15 cases） , inferior myocardial infarction （24 cases） , anterior and myocardial infarction （29 cases） for the study and assessed the parameters of global and regional left ventricular systolic and diastolic functions in the three groups. RESULTS （1）For left ventrieular global systolic function, left ventricular ejection fraction （LVEF） and peak ejection rate （PER） in anterior myocardial infarction group reduced significantly than those in control group and inferior myocardial infarction group respectively （P 〈 0.05 ）. （2）For left ventricular global diastolic function, peak filling rate （PFR） and first third filling fraction （1/3FF） in anterior myocardial infarction group reduced significantly than those in control group and inferior myocardial infarction group respectively （ P 〈 0.05 ）. （3）For left ventricular regional systolic function, left ventricular regional ejection fraction （LVREF） in anterior myocardial infarction group reduced significantly in two segments than that in inferior myocardial infarction group （ P 〈 0. 05 ）. （4）For left ventricular regional diastolic function, left ventricular regional first third filling fraction （LVR1/3FF） in anterior myocardial infarction group reduced significantly in two segments than that in inferior myocardial infarction group （P 〈 0.05）. CONCLUSION Anterior myocardial infarction has caused more severe damage to global and regional ventricular systoloic and diastolic functions than the damage caused by inferior myocardial infarction.