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阿司匹林抵抗产生机制的研究进展 被引量：1

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摘要 抗血小板药物阿司匹林广泛运用于心血管疾病的一级和二级预防中。临床上服用阿司匹林治疗的患者对该药物的反应性差异很大,有的患者的反应性很差甚至无反应,称之为阿司匹林抵抗。导致阿司匹林抵抗的机制,包括依从性差、药物间的相互作用和剂量不足等。通过进一步研究阿司匹林抵抗的机制,有助于优化抗血小板治疗。
作者 李佳蓓 黄岚
机构地区 重庆市第三军医大学附属新桥医院全军心血管内科研究所
出处 《心脏杂志》 CAS 2008年第5期638-640,共3页 Chinese Heart Journal
关键词 阿司匹林抵抗 血小板功能检测 基因多态性
分类号 R971.1 [医药卫生—药品]
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参考文献12

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二级参考文献9

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共引文献3

同被引文献1

  • 1Puleinelli FM, Riondino S. et al Persistent production of platelet thromboxane A2 in patients chronically treated with aspirin. J Throm b,Haem ost,2005,3(12) :2784-2789.

引证文献1

心脏杂志
2008年 第5期

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