颈动脉狭窄超声造影:与DSA相对照

Ultrasound contrast agent in evaluating the carotid atherosclerosis:contrasted with DSA

目的初步探讨超声造影检查在颈部动脉粥样硬化性狭窄疾病中的应用。方法应用超声造影观察36例颈部动脉粥样硬化患者造影前、后动脉斑块数量、形态特征等。应用彩色多普勒超声(CDFI)、超声造影检查测量动脉狭窄率,并与DSA进行对照。结果超声造影检查能发现更多造影前没有发现的动脉斑块、清晰显示动脉内-中膜厚度、勾勒出动脉斑块大小及形态。与DSA对照,应用CDFI、USCA诊断动脉粥样硬化所致颈部动脉闭塞的敏感性分别为55.6%、55.6%,特异性84.2%、94.7%,准确率75.0%、82.0%。结论超声造影检查为颈部血管疾病的诊断提供了一种安全、有效、创伤性小的诊断方法。

Objective To investigate the feasibility of intravenous contrast sonography in the diagnosis of carotid atherosclerosis. Methods Thirty-six patients with ICA, SCA or VA stenosis were investigated with ultrasound. Intima-media thickness （IMT） of these arteries and characteristics of plaques were measured in 36 patients before and after injection contrast agents, and the ratio of stenosis were calculated and contrasted with DSA. Results After injection of the contrast agent, IMT was depictted more clear than before, and more plaques were discovered. The morphology and structure of plaques could be observed using contrast agents. In detecting occlusion of carotid artery, SCA and VA, compared with DSA, the sensitivity was 55.6% and 55.6% for CDFI and ultrasound contrast agent （USCA）, while the specificity was 84.2%, 94.7% and the accuarcy was 75.0%, 82.0%, respectovely. Conclusion USCA can be used as an effective and safe method in the diagnosis of carotid artery diseases.