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遗传性秃发或少毛症研究进展 被引量:2

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摘要 遗传性秃发或少毛症是皮肤科一组比较少见的疾病。根据临床类型不同其具有特征性的临床表现各异。该组疾病的遗传方式可表现为常染色体显性遗传、常染色体隐性遗传和X连锁显性或隐性遗传。在分子遗传学方面,已有多个致病基因位点和/或致病基因被确定,如8p21、6p21、18p11、16q22、18q12、3q26、1p21、Xq13、5q32等致病基因位点和HR、CDH3、CDSN、DSG4、LIPH、ATP7A等基因。
出处 《中国麻风皮肤病杂志》 2008年第9期721-723,共3页 China Journal of Leprosy and Skin Diseases
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参考文献20

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同被引文献6

  • 1刘晨帆,边鹏飞,张莉.先天性秃发的遗传学研究进展[J].中国麻风皮肤病杂志,2005,21(4):291-293. 被引量:1
  • 2Van Steensel M, Smith FJD, Steijlen PM, et al. The gene for hypertrichosis of Marie Unna maps between D8S258 and D8S298 :exclusion of the hr gene by cDNA and genomic sequencing[J]. Am J Hum Genet, 1999,65:413 -419.
  • 3He PP,Zhang XJ,Yang Q,et al. Refinement of a locus for Marie Unna hereditary hypotrichosis to a 1.1 -cm interval at 8p21.3 [ J ]. Br J Dermatol,2004,150 ( 5 ) : 837 - 842.
  • 4Baumer A, Belli S, trueb RM, et al. An autosomal dominant form of hereditary hypotrichosis simplex maps to 18p11.32 -p11.23 in an Italian family [ J ]. Europ J Hum Genet, 2000,8:443 - 448.
  • 5Betz RC,Lee YA, Bygum A, et al. A gene for hypotrichosis simplex of the scalp maps to chromosome 6p21.3 [ J ]. Am J Hum Genet, 2000,66 : 1979 - 1983.
  • 6宋闯,范卫新.先天性秃发/少毛症的遗传学研究进展[J].临床皮肤科杂志,2014,43(12):753-758. 被引量:6

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