有机锡2-(3-吡啶甲基硫代)苯甲酸酯与2-吡啶硫代乙酸酯的合成、结构与抗真菌活性(英文)

Synthesis,Structure and Fungicidal Activity of Organotin 2-(3-Pyridylmethylthio)benzoate and (2-Pyridylthio)acetate

通过二乙基氧化锡、二丁基氧化锡以及三苯基氧化锡与2-(3-吡啶甲基硫代)苯甲酸和2-吡啶硫代乙酸的反应,3个四核有机锡羧酸酯以及2个单核三苯基锡羧酸酯被合成。它们的结构通过X-射线单晶衍射结构分析得到确证。生物活性测试表明,四核二丁基锡2-吡啶硫代乙酸酯以及单核三苯基锡2-(3-吡啶甲基硫代)苯甲酸酯对西瓜炭疽病菌、花生褐斑以及苹果轮纹菌等具有高的抑制活性。

Three dimeric complexes {[2-（3-PyCH2S）C6H4CO2SnR2]2O}2 and {[（2-PySCH2CO2）SnR2]2O}2 （Py=pyridyl） as well as two monomeric complexes （2-PySCH2CO2）SnPh3 and [2-（3-PyCH2S）C6H4CO2]SnPh3 have been synthesized by the reaction of 2-（3-pyridylmethyhhio）benzoic acid or （2-pyridylthio）acetic acid with R2SnO （R=Et or ^nBu） and （Ph3Sn）2O. Their structures have also been confirmed by X-ray single crystal diffraction. Preliminary in vitro tests for fungicidal activity show that complexes {[（2-PySCH2CO2）SnBu^n2]2O}2 and [2-（3-PyCH2S）C6H4CO2]SnPh3 display high activity to Colletotrichum lagenarium, Cercospora arachidicola and Physolospora piricola in a low concentration. CCDC： 685778, 2; 685777, 4.