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不同产地黄连的体外抑菌活性与镇静作用 被引量:4

COMPARISON OF IN VITRO BACTERIOSTATIC AND SEDATIVE ACTIONS OF RHIZOMA COPTIDIS FROM DIFFERENT AREAS
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摘要 本文比较了不同产地的7种黄连与小檗碱的体外抑菌活性及镇静作用。体外抑菌活性表明,黄连5mg/ml与小檗碱0.5mg/ml比较,除四川巫山及四川石柱黄连外,其它均优于小檗碱。镇静作用表明,各种黄连及小檗碱与生理盐水比较,均有显著差异(p<0.05)而与小檗碱比较无显著差异。 We have compared the in vitro bacteriostatic and sedative acti- ons of seven Rhizoma coptidises from different areas and Berberine. It was found that majority of Rhizoma coptidises (5mg/ml) except drugs No. 6 and No. 7 are more effective than Berberine(0.5mg /ml) in vitro bacteriostatic test. AII Rhizoma ceptidises and Berberine could significantly decrease the spontaneous activities of mice (p<0.01, as compared with control) , but the difference be- tween Rhizoma coptidises and Berberine was not significant.
出处 《华西药学杂志》 CAS CSCD 北大核心 1990年第3期168-170,共3页 West China Journal of Pharmaceutical Sciences
关键词 黄连 抑菌活性 镇静作用 Rhizoma coptidis Berberine Minimum inhibitory concentration (MIC) Sedative action
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  • 1陈淑清,余立江,江帆,蔡平,肖倬殷.竹节参总皂甙的镇痛、镇静、抗惊及解痉作用和毒性试验[J]华西药学杂志,1987(02).

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