摘要
本文比较了不同产地的7种黄连与小檗碱的体外抑菌活性及镇静作用。体外抑菌活性表明,黄连5mg/ml与小檗碱0.5mg/ml比较,除四川巫山及四川石柱黄连外,其它均优于小檗碱。镇静作用表明,各种黄连及小檗碱与生理盐水比较,均有显著差异(p<0.05)而与小檗碱比较无显著差异。
We have compared the
in vitro bacteriostatic and sedative acti-
ons of seven Rhizoma coptidises from
different areas and Berberine. It was
found that majority of Rhizoma coptidises
(5mg/ml) except drugs No. 6 and No. 7
are more effective than Berberine(0.5mg
/ml) in vitro bacteriostatic test. AII
Rhizoma ceptidises and Berberine could
significantly decrease the spontaneous
activities of mice (p<0.01, as compared
with control) , but the difference be-
tween Rhizoma coptidises and Berberine
was not significant.
出处
《华西药学杂志》
CAS
CSCD
北大核心
1990年第3期168-170,共3页
West China Journal of Pharmaceutical Sciences
关键词
黄连
抑菌活性
镇静作用
Rhizoma coptidis Berberine Minimum inhibitory concentration (MIC) Sedative action
