输血对肿瘤外科手术疗效的影响

Effect of Blood Transfusion on the Sugery Outcome of Tumor

近年来,人们发现围术期异体输血对于人体免疫系统具有显著的抑制作用。在对肾移植患者研究表明,异体输血可以通过抑制患者免疫功能延长其移植器官存活期,而免疫水平低下,特别是长期接受异体输血或肾移植的患者,其恶性肿瘤的发生率也明显增加。因而,有学者推测围术期异体输血可能影响恶性肿瘤切除术后患者的生存期长短,并且这已在直肠癌和乳腺癌患者中得到初步证实。随着医学技术的不断进步和人们对肿瘤患者手术输血影响患者术后生存期的日益关注,也必将促进成分输血、自体输血等输血新理论和新技术的不断发展。

In recent years, some researchers find that peri-operative period variant blood transfusion has a noticeable inhibitory action to immunologic system In the patients with kidney transplantation, variant blood transfusion can postphone the survival time of transplanted organs by inhibiting immune function of patients. Patients with lower immune function, especially the patients accepting variant blood transfusion or renal transplantation have the obviously increased incurrence of tumor. So it suggestes that variant blood transfusion maybe affect the survival time of patients after surgery, which has been initially testified in the patients with rectal cancer and breast cancer. With the development of medical techniques, more attention has been paid to influence of blood transfusion during operation on the survival time of patients after this kind of surgery,which also will promote the development of new conception and new techniques, such as component blood transfusion, antohemotransfusion and so on.