防蛀剂中间体炔戊菊酯-醚化β-环糊精包合物的制备工艺

STUDY ON THE NEW ANTIFUNGAL AGENT ABOUT ETHERIFIED β-CYCLODEXTRIN INCLUSION TECHNOLOGY FOR TCMTB

通过单因素实验研究了基于饱和溶液法用醚化β-环糊精包合防蛀剂2-(硫氰基甲基硫代)苯并噻唑(TCMTB)的工艺.当醚化β-环糊精投入量为16g时,通过考察TCMTB的加入量、包合时间、包合温度、搅拌速度的影响,得到了包合物的最佳包合条件:TCMTB加入量为0.8g、包合时间为2h、包合温度为45℃、包合搅拌速度为400r/min.此条件下可获得较高的包封率产物,并对产物进行了表征.

This paper takes a research on β-cyclodextrin inclusion technology for 2-（benzothia- zolylthio） methyl ester through single factor experiment by saturated solution method. When the adding amount of etherified ffcyclodextrin is 16 g, by changing the adding amount of TC- MTB, inclusion time and inclusion temperature, we got the optimal conditions about the inclusion complex as follows： the adding amount of TCMTB was 0.8 g,inclusion time was 2 h, inclusion temperature was 45 ℃ and stirring speed was 400 r/min. It has high inclusive ratio under these conditions and the testimony of inclusion complex were given by TGA.