用XIXA法对大鼠糖尿病性白内障锌含量改变的研究

Study on Change in Zinc Concentration for Diabetic Cataractous Lenses in Rats by Means of ⅩⅨA

在链脲佐菌素所致SD系大鼠糖尿病性白内障期间,用同位素激发X荧光分析(XIXA)法测定晶状体的Zn及K、Ca、Mn、Fe、Cu、Pb、Se等元素含量的改变。结果发现:在糖尿病性白内障的发病期间,Zn和Fe的含量显著增加;K含量显著降低;其他受检元素无显著变化。

The SD rats were injected with strepto-zotocin to induce diabetic cataract. ElementZn as well as K, Ca, Mn, Fe. Cu, Pb,Se, etc. in the eye lenses was daterminedby means of X-ray induced X-fluores-cence analysis(XIXA). Compared to valuesfor normal healthy rats, the concentrationof Zn and Fe in the cataractous lenses in-creased, the conentration of K decreased,and that of the others did not change pro-minentlly. The change in Zn conentrationwas probably to meet the deeds of the me-tabolic adjustment in the eye lenses,whichwould not be the reason for directly induc-ing diabetic cataract.