金顶侧耳对小鼠小肠推进功能的研究

Research into the Effects of Pleurotus citrinopileatus on the Function of Rat's Stomache and Intestinal movement

分别以正常、新斯的明负荷、肾上腺素负荷小鼠为实验研究模型,采用炭末小肠推进试验法,探索金顶侧耳对小鼠小肠推进功能的影响。结果表明,金顶侧耳提取液1次性ig给药3.00g·kg-1可显著促进正常小鼠的小肠运动(P<0.01);对新斯的明负荷引起的小鼠小肠推进亢进有显著的拮抗作用(P<0.05),对肾上腺素负荷引起的小肠推进抑制无明显的拮抗作用(P>0.05)。

Apply the charcoal powder in healthy mice, neostigmine-treated mice and mice with spleen deficiency to test the effects of Pleurotus citrinopileatus on the function of rat ＇ s stomaehe and intestinal movement. As a result, an oral administration of Pleurotus citrinopileatus liquid at a single dose was found to significantly promote gastrointestinal movement in a dose-dependent manner in healthy mice（P〈0.01）; a remarkable antagonistic effect of Pleurotus citrinopileatus liquid against the increase of gastrointestinal movement induced by neostigmine was observed in mice （P〈0.05）, no obvious antagonistic effect was found on the restraint function of SIP induced by adrenaline （p〉0.05）.