联合治疗轻中度溃疡性结肠炎30例临床观察

Clinical Observation of 30 Mild and Moderate UC Cases Treated by Combination Treatment

目的:探讨在柳氮磺胺吡啶(SASP)基础上联合法莫替丁和麦滋林-S治疗轻中度溃疡性结肠炎(UC)的临床疗效。方法:将61例UC病人随机分为联合用药组(30例)和对照组(31例),所有病人均口服SASP,联合用药组同时加用法莫替丁、麦滋林-S。结果:总有效率、症状平均缓解时间、肠镜检查、病理组织学检查在组间比较有显著性差异(P<0.05),联合用药组疗效优于对照组。结论:联合治疗轻中度溃疡性结肠炎疗效理想,副作用少,值得推广。

Objective： To research the effect of ulcerative colitis （UC） treated by the combination of famofidine with marzulene - S and on the basis of SASP. Methods： 61 patients who were diagnosed as mild to moderate, active phase UC were divided into combined medication group（ n =30）and contrast group（ n = 31 ） randomly. All patients were taken SASP , while combined medication group was received famotidine and marzulene - S at the same time. Results： The total efficiency , the average time of symptom relief, the results of colonoscopy, the histopathological examination had significant differences （ P 〈 0.05 ） between two groups. Conclusion： The combination medication treatment of mild and moderate UC is satisfatory and safe, it is worth spreading widely.