北冬虫夏草对皮肤细菌感染的体外抗菌活性观察

Observation on Antibiotic Activity in vitro of Cordyceps Militaris on Bacteria Infection of Skin

目的:探索北冬虫夏草(蛹虫草)对皮肤细菌感染的体外抗菌活性。方法:用纸片琼脂扩散法进行体外药敏试验。结果:北冬虫夏草的萃取液(1:10 mg/mL)体外药物试验,对25株金黄色葡萄球菌敏感率为88.00%,19株化脓性链球菌敏感率为68.42%,8株绿浓杆菌敏感率为75.00%。结论:北冬虫夏草的萃取液对金黄色葡萄球菌、化脓性链球菌、绿杆菌都有不同程度的抗菌活性,并与其浓度呈线性关系.

Objective： To search for antibiotic activity in vitro of Cordyceps militaris on bacteria infection of skin. Methods： Detecting susceptibility in vitro of tested bacteria on Cordyceps militaris by disk diffusion methods. Results： Antibiotic activities in vitro of Cordyceps militaris on Staphyloccocus aureus Rosenbach, streptococcus pyogenes and Pseudomonas aeruginosa are 88.00%, 68.42% and 75.00%, respectively. Conclusion： There are different antibiotic activities in vitro of Cordyceps militaris extract on Staphyloccocus aureus Rosenbach, streptococcus pyogenes and Pseudomonas aeruginosa. There appears linear relationship between extract concentration ofCordyceps militaris and the above bacteria.