2Zhang L,Li H,Zhao H,et al. Retrospective analysis of 1312 patients with haemophilia and related disorders in a single Chinese institute[J]. Haemophilia,2003,9 (6) :696 - 702.
5Wang T, Zhang L, Li H, et al. Assessing health-related quality-of- life in individuals with haemophilia in China [ J ]. Haemophilia, 2004,10(4) :370 -375.
6Yang R, Wang H, Han ZC. Polymorphisms associated with factor Ⅸ gene in Chinese people[ J]. Haemophilia, 1999,5 (6) :453 - 456.
7Fang Y,Wang X, Dai J,et al. A rapid multifluorescent polymerase chain reaction for genetic counseling in Chinese haemophilia A families [ J ]. Haemophilia,2006,12:62 - 67.
8Liang Y, Yan M, Xiao B, et al. Analysis of intron 1 factor Ⅷ gene inversion for direct diagnosis in patients with severe haemophilia A in China[ J ]. Prenat Diagn ,2008,28 ( 2 ) : 160 - 161.
9Shi J, Zhao Y, Wu J, et al. Safety and efficacy of a sucrose-formulated recombinant factor Ⅷ product for the treatment of previously treated patients with haemophilia A in China [ J ]. Haemophilia, 2007,13(4) :351 -356.
10Lu DR, Zhou JM, Zheng B, et al. Stage Ⅰ clinical trial of gene therapy for hemophilia B [ J]. Sci China B, 1993,36 ( 11 ) : 1342 - 1351.
6Aronstam A,Rainsfad SG,Painter MJ,et al.Patterns of bleeding in adolescents with severe hemophilia A[J].Br Med J,1979,1(2):469-470.
7Wang T,Zhang L,Li H,et al.Assessing health related quality-of-life in individuals with haemophilia in China[J].Haemophilia,2004,10(7):370-375.
8Aledort LM,Haschmeyer RH,Pettersson H.A longitudinal study of orthopaedic outcomes for severe factor Ⅷ deficient haemophilia.The Orthopaedic Outcome Study Group[J].J Intern Med,1994,236(10):391-399.
9Nilsson IM,Berntorp E,Lofqvist T,et al.Twenty-five years' experience of prophylactic treatment in severe haemophilia A and B[J].J Intern Med,1992,232(7):25-32.
10Funk M,Schmidt H,Pons S,et al.Radiological and orthopedic score in pediatric hemophilic patients with early and late prophylaxis[J].Ann Hematol,1998,77(10):171-174.
