摘要
本研究采用配对设计的方法,对接触组和对照组人员分别测定了血和尿中镉、钙和β2-微球蛋白(β2-MG)含量,并测定尿N-乙酰-β-D-氨基葡萄糖苷酶(NAG)活性和总蛋白含量。结果显示,接触组尿镉、钙、β2-MG、总蛋白含量和NAG活性及血镉含量都高于对照组。尿NAG活性与血和尿中镉、钙、β2-MG和总蛋白含量均呈正相关,表明尿NAG是监测镉引起肾损害的敏感指标之一。
The content of cadmium(Cd),calcium(Ca),β2microglobulin(β2MG) in blood and urine,and the urinary N-acetyl-β-D-glucosaminidase(NAG) activity and total protein content were respectively determined in exposure and control groups in this study.The results showed that the content of urinary Cd, Ca,β2MG,total protein, and NAG activity,and Cd content in blood in exposure group were higher than that in control group.Urinary NAG activity was positively correlated with Cd content in blood and urine,urinary Ca,β2MG and total protein content.It was showed that NAG is one of the sensitive indexes of renal damage.
基金
贵州省科委科研基金