脑卒中患者的颈动脉粥样硬化病变比较研究

COMPARISON OF CAROTID ATHEROSCLEROSIC LESIONS IN STROKE PATIENTS

为了探讨颈动脉粥样硬化程度、性质特点和脑卒中的关系，对14例脑卒中病例（脑出血7例，脑梗塞7例）的颈动脉进行了病理观察及形态定量分析。结果显示：脑出血病灶侧颈动脉存在明显粥样硬化性狭窄，P＜0．05，脑梗塞患者的颈动脉粥样硬化程度重于脑出血，尤以颈内动脉表现为著，P＜0．05，脑梗塞患者的颈动脉粥样硬化斑块具备不稳定的组织学特性，为夹层动脉瘤，动脉内膜溃疡，附壁血栓或质地松散，密度不均易脱落的斑块。该研究提示：颈动脉狭窄的程度与脑出血或脑梗塞均相关，若粥样硬化斑块为不稳定状态，则是脑梗塞发病的重要病因。

In order to investigate the relationship between the properties of carotid atheromatous lesions and cerebralstrokes, 14 autopsy cases were studied, including seven cases of cerebral hemorrhage (CH), and seven cases of cerebral infarction (CI). The results show that the carotid arteries on the same side had obvious stenosis (P < 0.05).The degree of narrowing was more severe in CI than in CH, especially in the internal carotid artery (P< 0.05). InC1, the plaque lesions of carotid arteries exhibited unstable morphological properties. The results suggest that thedegree of stenosis is related to CH and CI. If the morphology of the plaque lesions is unstable, CI is the source.