摘要
多囊卵巢综合征是青春期及育龄妇女最常见的妇科内分泌病。多囊卵巢综合征病人不孕的主要原因是不排卵,但自发排卵或经药物纠正不排卵因素病人总体妊娠率仍不高。近年研究推测,病人体内复杂的内分泌和代谢环境影响了子宫内膜稳态,也可导致病人生育力减弱和不良妊娠。
The polycystic ovarian syndrome （PCOS） is the most frequent endocrinopatiny in women of childbearing age. The main cause of infertility in polycystic ovarian syndrome is anovulation. But PCOS patients with spontaneous ovulation or treated with ovulation induction do not get pregnant as expected. It is speculated that the abnormal tissue homeostasis exhibited by the endometrium from PCOS patients with ovulation may interfere with their endometrial receptivity. This article reviews the molecular mechanisms known to underlie metabolic abnormalities in endometrium of PCOS related to infertility.
出处
《内蒙古医学院学报》
2008年第4期301-304,共4页
Acta Academiae Medicinae Neimongol
关键词
多囊卵巢综合征
子宫内膜
不孕
polycystic ovarian syndrome
endometrium
infertility
