3Peter Boor, Andrzej Konieczny, I.uigi Villa, et al. Complement C5 mediates experimental tubulointerstitial fibrosis[J]. J Am Soc Nephrol, 2007, 18 (5): 1508 -1515.
4Zahedi R, Braun M, Wetsel R A, et al. The C5α re ceptor is expressed by human renal proximal tubularepithelial cells[J]. Clin Exp Immunol, 2000, 121(2):226-233.
5Yang J, Liu Y. Dissection of key events in tubular epi thelial to myofibroblast transition and its implications in renal interstitial fibrosis [J]. Am J Pathol, 2001, 159 (4) :1465-1475.
6Zwirner J, Fayyazi A, Gotze O. Expression of the anaphylatoxin C5α receptor in non-myeloid cells[J]. Mol Immunol,1999,36(13 14) :877-884.
7Wilmer WA, KaumayaPT, EmberJ A, etal. Recep tors for theanaphylatoxin C5α (CD88) on human mesangial cells[J]. J Immunol, 1998, 160 (11): 5646 -5652.
8Addis-Lieser E, Kohl J, Chiaramonte M G. Opposing regulatory roles of complement factor 5 in the development of bleomycin induced pulmonary fibrosis[J]. J Immunol,2005,175 (3) :1894-1902.
9PN Monk, Scola AM, Madala P, et al. Function, structure and therapeutic potential of complement C5a receptors. British Journal of Pharmacology ,2007,152 (4) :429 - 448.
10Mery L , Boulay F. The NH2 - terminal region of C5aR but not that of FPR is Critical for both protein transportand ligand binding. J Biol Chem, 1994,269(5 ) :3457 - 3463.