^(99m)Tc-甲氧基异丁基异腈首次通过法心室显像评价左心室收缩功能

The Application of FirstPass Method in Radionuclide Angiocardiographic Assessment of Left Ventricular Systolic Function with Technetium99m Methoxy Isobutyl Isonitrile

应用９９ｍＴｃ－甲氧基异丁基异腈（ＭＩＢＩ）对２９例受检者进行首次通过法心室显像，测定左室射血分数（ＬＶＥＦ），并与同期平衡法心室显像测得的ＬＶＥＦ进行相关分析。结果：首次通过法和平衡法心室显像测得的ＬＶＥＦ分别为（４６．５±１６．７）％、（４９．１±１６．１）％（Ｐ＞０．０５）。相关分析结果显示，二者有明显的相关（ｒ＝０．７８７，Ｐ＜０．０１）。结果表明：９９ｍＴｃ－ＭＩＢＩ为心肌显像剂，采用首次通过法心室显像，在观察心肌血流改变的同时，可准确可靠地评价左室收缩功能状态。

wenty-nine cases were studied by firstpass radionuclide angiocardiography with Tc99mmethoxy isobutyl isonitrile (MIBI). Left ventricular ejection fractions (LVEF) obtained from this method and from equilibrium ventricular angiography were measured and compared with each other. The LVEF was 46.5%±16.7% for the former, and 49.1%±16.1% for the latter (P>0.05). Regressive analysis showed that correllation between these two methods was significant (r=0.787, P<0.01). The results indicated that Tc99mMIBI could be used accurately and reliably to evaluate left systolic ventricular function by firespass radionuclide angiocardiography, and to observe the changes of myocardial blood flow simultaneously, though it is an agent for myocardial perfusion imaging.