环氧氯丙烷合成工艺研究

Study of synthesis of epichlorohydrin

采用单因素实验和正交试验相结合的方法,研究了由二氯丙醇和Ca(OH)2合成环氧氯丙烷的环化反应,得到了较佳工艺条件:n(1/2Ca(OH)2)/n(二氯丙醇)=1.2,50℃反应20 s,在此条件下产物的平均收率达93.1%。

Preparation of epiehlorohydrin by cyclic reaction of diehloropropanol with Ca （OH）2 was studied. Optimal conditions for the preparation were obtained by a combination method of single - factor test and orthogonal experiment. Experimental results showed that the optimal conditions for the cyclization of dichloropropanol are as follows： mole ratio of 1/2Ca （OH）2 to dichloropropanol, 1.2： 1; reaction temperature, 50 ℃; and reaction time, 20 s. Under the optimal reaction conditions, the yield of epichlorohydrin achieves 93.1%.