红花黄色素注射液治疗缺血性中风60例临床疗效观察

Clinical effect of Honghuahuangsesu injection on ischemic apoplexy

目的:观察红花黄色素注射液对脑梗死的治疗作用。方法:60例患者随机分为治疗组即Ⅰ组30例,对照组即Ⅱ组30例。Ⅰ组应用红花黄色素注射液100mg加入0.9氯化钠注射液250mL内静脉滴注,Ⅱ组应用银杏达莫注射液20mL加入0.9生理盐水250mL内静脉滴注,均qd,15d为一疗程,进行随机对照。结果:红花黄色素注射液对脑梗死临床有效率达93.3,与银杏达莫注射液对照差异有显著性(P<0.05)。治疗前后2组血液流变学以及SOD、MDA变化差异均有显著性。红花黄色素对气虚血淤型中风疗效最佳。结论:红花黄色素注射液对脑梗死具有较好的治疗作用。

OBJECTIVE To investigate the clinical effect of Honghuahuangsesu injection for ischemic apoplexy. METHODS The 60 patients with ischemic apoplexy were randomly divided into the therapeutic group （group Ⅰ 30 cases） and the control group （group Ⅱ , 30 cases）. Group Ⅰ was treated by Ⅳ drip of Honghuahuangsesu 100 mg in 250 mL of 0. 9% physiological soline. Group Ⅱ was treated by Ⅳ drip of Yinxingdamo injection 20 mL in 250 mL of 0. 9% physiological saline. Both groups were given drugs oncea day, 15 days constituting a single therapeutic course. The study was carried out by using the ischemic apoplexy con-trast method. RESULTS The effective rate of Honghuahuangsesu was 93.3%. There was obvious difference in effective ratebetween group Ⅰ and group Ⅱ （P〈0. 05）. The limbs articulation and combination blood plasma functions and the level of SOD and MDA before and after treatment were evaluated and compared. Both groups had obvious significance. Hong- huahuangsesu showed a remarkable effect for qi vacuity bloodstasis. CONCLUSION Honghuahuangsesu has been used for the treatment of ischemic apoplexy with favorable results.