^(18)F-FDG PET显像在头颈肿瘤诊断中的作用评价

The role of ^(18)F-FDG PET in the identification of head and neck primary tumors

目的:比较^(18)F脱氧葡萄糖正电子发射体层显像(^(18)F-FDG PET)与CT/MRI检查在头颈肿瘤诊断中的应用价值。方法:54例头颈肿瘤患者在术前2周分别进行PET与CT、MRI检查,以病理结果为金标准,分析2种方法在敏感度、特异度及准确率方面的差异,采用SPSS13.0软件包对数据进行X^2检验。结果:PET和CT、MRI分别准确判断了54例肿瘤中的48和43例,PET在敏感度、特异度及准确率方面分别比CT、MRI高7.4%、15.3%和9.3%,但差异均无显著性。结论:PET在头颈肿瘤诊断的敏感度、特异度及准确率方面优于CT、MRI,但结果无统计学差异。

PURPOSE： To evaluate the role of ^18F-FDG PET in the identification of head and neck neoplasms in contrast to CT/MRI. METHODS： Fifty four patients with head and neck primary tumors underwent PET and CT/MRI two weeks before surgery. Histopathologie analysis was used as the gold standard for diagnosis. Difference of sensitivity, specificity and accuracy between PET and CT/MRI was analyzed using SPSS13.0 software package for Chi-square test. RESULTS： PET correctly identified the primary tumors in 48/54 patients and CT/MRI identified the primary tumors in 43/54 patients. The sensitivity, specificity and accuracy of PET for the identification of primary tumors were 7.4% ,15.3% and 9.3%, higher than those of CT/MRI, but not significantly. CONCLUSIONS： The sensitivity ,specificity and accuracy of PET for identification of head and neck primary tumors is higher than those of CT/MRI, but the difference was not statistically significant. Supported by Medical Scientific Research Foundation of Guangdong Province （Grant No.A2002032）, and Key Project of Science and Technology Program of Guangdong Province （Grant No.2005B30901015）.