新型强脉冲光治疗黄褐斑的临床体会

Application of a novel intense pulsed light device on melasma lesions

目的:探讨强脉冲光治疗面部黄褐斑的疗效及安全性。方法:256例黄褐斑患者接受了4次强脉冲光治疗。于治疗前、后采用分光光度计测定黄褐斑处的L值,由医生对治疗效果进行综合评估,并由患者进行满意度评估。结果:经过4次治疗,皮肤的亮度(L值)显著提升,医生评估78.9%的患者获得了超过50%的改善,71.1%的患者对治疗效果满意或非常满意;副作用主要为轻微的一过性红斑和炎症后色素沉着。结论:强脉冲光技术可以有效地治疗黄褐斑,副作用非常轻微。

Objective To investigate the long-term efficacy and safety of a new intense pulsed light （IPL） device in the treatment of melasma lesions. Methods Two hundred and fifty-six women with refractory melasma were enrolled in this study. Subjects received a total of four IPL treatments. The efficacy was evaluated using the spectrophotometry （L value）, a percentage category scale, and a 4 point satisfaction scale before and after each session. Results Mean L value increased significantly from the baseline to the follow up visits of each treatment. Two hundred and two patients （78.9%） obtained 51%-100% improvements, according to the over-all evaluation by dermatologists. Over 70% patients considered their results satisfactory or very satisfactory. Adverse reactions were mainly transient erythema and postinflammatory hyperpigmentation. Conclusions IPL treatment is a good option for patients with melasma. Adverse actions were minimal.