尿路感染病原菌分布及耐药性分析

Distribution of pathogens and antibiotic resistance analysis in urinary infection

目的:探讨尿路感染病原菌的分布及耐药性特征,为临床合理应用抗生素提供依据。方法:常规细菌培养方法,细菌鉴定应用MicroScan WalkAway-40全自动微生物分析仪及常规法鉴定;药敏试验采用K-B纸片扩散法。结果:尿路感染以大肠埃希菌检出率最高(45.7%),其余为肠球菌属(15.6%)、葡萄球菌属(13.6%)、肺炎克雷伯菌(6.6%)、铜绿假单胞菌(5.0%)等。大肠埃希菌和肺炎克雷伯菌对亚安培南、头孢哌酮/舒巴坦、哌拉西林/他唑巴坦的敏感率>90%,对氨苄西林、左旋氧氟沙星的敏感率<50.0%。结论:重视尿路感染病原菌的耐药性检测,对控制医院感染、合理使用抗生素具有重要意义。

Objective：To investigate the distribution of pathogens and resistance characteristic in urinary infection and provide basis for clinicians to select antibiotics correctly.Methods：Flora was identified with the MicroScan WalkAway-40 automatic identifier,and bacteria-susceptibility test was operated with Kirby-Bauer method.Results：Escherichia coli was the most common becteria in the urinary tract infections（45.7%）,then enterococcus（15.6%）,Staphylococcus（13.6%）,Klebsiella pneumoniae（6.6%）,Pseudomonasaeruginosa（5.0%）,respectively.E.coli and K.pneumoniae were sensitive to imipenem cefoperazone-sulbactam,piperacillin-tazobactam was higher than 90.0%.But to ampicillin,levofloxacin was lower than 50.0%.Conclusion：Much attention should be paid to resistance detection in urinary infection.It is important to control nosocomial infection and select antibiotics correctly.