上海市长风社区糖尿病高危人群代谢综合征患病情况调查

Prevalence of metabolic syndrome in population at high-risk for diabetes in Changfeng community of Shanghai

目的了解社区糖尿病高危人群代谢综合征（MS）的患病情况。方法对上海市长风社区982名40～79岁、有糖尿病高危因素、无明确糖尿病史的社区居民，进行问卷调查及相关检查，观察MS的检出情况及其临床特征。结果MS检出率为44．6％（438／982）；男性MS检出率低于女性[34．5％（97／281）与48．6％（341／701），P〈0．01]，女性MS的检出率随着年龄的增加而增高（P〈0．01），但男性MS检出率和年龄的相关性无统计学意义（P〉0．05）。MS组分分布由高到低依次为高血压66．5％（653／982），腹型肥胖62．8％（617／982），低高密度脂蛋白胆固醇（HDL-C）49．4％（485／982），高甘油三酯（TG）46．0％（452／982）和空腹血糖增高35．7％（351／982）。同时有腹型肥胖以外3个及3个以上MS组分者55．9％（245／438）。结论社区糖尿病高危人群中有较高的MS检出率，MS患者中以同时有较多的心血管危险因素者居多。

Objective To investigate prevalence of metabolic syndrome （MS） in population at high-risk for diabetes in Changfeng community of Shanghai. Methods Totally, 982 persons aged 40 - 79 years without previous history of diabetes, but with risk factors for diabetes from Changfeng community in Shanghai were screened by questionnaire, physical examinations, lipid profile and oral glucose tolerance test. Prevalence of MS and its clinical characteristic were observed. Results Overall prevalence of MS was 44.6% （438/982） in Changfeng community, significantly higher in women of 48. 6% （341/701） than that in men of 34. 5% （97/281） （P 〈0. 01 ）. Prevalence of MS increased with age in women （P 〈0. 01 ）, but not in men （P 〉 0. 05 ）. Components of MS ranking from high to low were hypertension of 66. 5% （653/982）, abdominal obesity of 62. 8% （617/982）, decreased high-density lipoprotein-cholesterol （HDL-C） of 49.4% （485/982）, increased triglyceride （TG） of 46. 0% （452/982） and increased fasting glucose of 35.7% （351/982）. There were 55.9% （245/438） of MS patients with three or more MS components in addition to abdominal obesity. Conclusions Prevalence of MS is higher in community population at high-risk for diabetes and more than haft of the MS patients have three or more risk factors for cardiovascular disease.