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吉西他滨联合希罗达治疗胰腺癌临床观察 被引量:4

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摘要 采用吉西他滨(GEM)联合希罗达治疗晚期胰腺癌患者30例,希罗达1250mg/m^2口服,第1~14天,休息7d后重复治疗;GEM1000mg/m^2静滴,第1、8天;至少接受2个周期化疗后进行临床评价。结果近期客观有效率26.67%,疼痛缓解率、生活状态改善率均为53.33%,体质量改善率40.00%。主要不良反应为骨髓抑制、外周神经毒性及胃肠道反应。认为GEM联合希罗达治疗晚期胰腺癌近期疗效较高,毒性较低,能显著提高患者的生存质量。
出处 《山东医药》 CAS 北大核心 2008年第34期80-81,共2页 Shandong Medical Journal
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