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代谢和免疫相互作用稳态--复杂性科学视角下的营卫解读 被引量:29

Studying homeostasis from interaction between metabolism and immune system:revelation of ying-wei theory based on complexity science
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摘要 免疫炎症和代谢调节高度统一,功能上相互依赖,这种免疫和代谢之间的相互作用可以被看作机体稳态调节的核心机制。只有把免疫炎症和营养代谢的非线性相互作用作为一个整体来研究,刻画其状态的变化,才能有效的调控它。可是由于非线性防御系统的超级复杂性,系统生物学从下向上的研究在这方面存在着几乎不可克服的困难。中医营卫学说从整体出发,对免疫和代谢相互作用的状态变化进行了有效的刻画,这中间研究的思路、方法以及记载在历代文献中的丰富经验是弥足珍贵的。 The interaction between immune response and metabolic regulation can be viewed as a central homeostatic mechanism, dysfunction of which will lead to many diseases. This nonlinear interaction ,which has the characteristic of super-complexity, can't be controlled unless it is studied as a holism and the change of condition is researched .To study this homeostasis, bottom-up method used in system biology is limited. Ying-wei theory of TCM uses another method to describe different states of metabolic and immune systems effectively. The unique approaches and rich experiences applied in TCM are of great value.
作者 周东浩 房辉
机构地区 河北医科大学
出处 《中华中医药杂志》 CAS CSCD 北大核心 2008年第10期856-859,共4页 China Journal of Traditional Chinese Medicine and Pharmacy
关键词 营卫 系统生物学 免疫 代谢 Ying-wei System biology Immune system Metabolic system
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