连续性血液滤过治疗烧伤合并中毒性肠麻痹的临床评价

Treatment of burn merging intoxication enteroparalysis with continuous hemofiltration

目的探讨连续性静脉-静脉血液滤过（CVVH）治疗烧伤合并中毒性肠麻痹的临床疗效。方法回顾性分析27例烧伤中毒性肠麻痹患者，随机单盲分为对照组12例，采用常规治疗；CVVH组15例，采用常规治疗＋CVVH。分别观察2组患者在治疗前后血钾、白细胞、体温和肠鸣音的变化。结果15例烧伤合并中毒性肠麻痹患者用CVVH治疗后，相关指标、有效率、治愈率和病死率与对照组比较有统计学意义（P〈0．01）。结论连续性血液滤过治疗烧伤中毒性肠麻痹时能有效清除炎症介质，调节水、电解质和酸碱平衡，能使低血钾状态下的中毒性肠麻痹症状得到较快改善，提高抢救成功率。

Objective To observe the clinical effects of continuous veno-venous hemofiltration（CVVH） on bum merging with intoxication enteroparalysis. Methods Twenty-seven patients were randomized into CVVH group （15 cases） and control group （12 cases）. The CVVH group received routine therapy plus CVVH. The control group received routine therapy only. Indexes like kalmia, WBC, body-temperature and bowel sound were observed. Results After CVVH therapy, the CVVH group showed significant increase in the corresponding indexes, higher effective rate, and lower mortality rate. Conclusion CVVH therapy effectively reduces proinflammatory mediators, improves water, electrolyte and acid-base balance, improves hypokalemia enteroparalysis. As a result, it increases the success rate of resuscitation.