经纤维支气管镜不同取材方法对肺癌诊断的临床研究

Diagnostic value of different sample selection methods of fibrobronchoscope in lung cancer

目的探讨纤维支气管镜下不同取材方法对肺癌的诊断价值。方法对168例肺癌患者纤维支气管镜检查结果进行回顾性分析,比较钳检、刷检、冲洗与联合取材对肺癌诊断的阳性率。结果钳检、刷检、冲洗的阳性率分别为80.0%,70.8%,68.5%,钳检并刷检与三者联合取材的阳性率分别为91.1%和97.0%。联合取材阳性率显著高于单一取材(P<0.01)和钳检并刷检(P<0.05)。取材诊断总阳性率以增生型97.8%为最高,浸润型94.6%,外压型66.7%。结论纤维支气管镜联合取材可提高肺癌诊断率。

Objective To evaluate diagnostic value of different sample selection methods of fibrobronehoscope in lung cancer. Methods The results of fiberobronchoseopy were analyzed retrospectively in 168 cases of pulmonary carcinoma,and diagnostic positive rate were compared among protractor biopsy, brush biopsy,lavation and allied sampling. Results The positive rate of protractor biopsy, brush biopsy and laration were 80.0% ,70.8% and 68.5%, respectively,the positive rate of protractor biopsy combined with brush biopsy and allied sampling were 91.1% and 97.0%. The positive rate of allied sampling was higher than that of each of three methods （ P 〈 0. 01 ） and protractor biopsy combined with brush biopsy （P 〈0.05）. The total diagnostic positive rate of the specimen was high in hyperplasia type （97.8%） and second in infiltrating type（94.6% ） and exophytie type（ 66.7% ）. Conclusion Allied sampling by fiberubronchoscope can increase the diagnostic positive rate of pulmonary carcinoma.