成釉细胞瘤的临床病理及其与复发的关系

Study on relationship between clinicopathology and recurrence of ameloblastomas

目的对比分析成釉细胞瘤不同类型的临床病理特点及其与复发的关系。方法对228例成釉细胞瘤患者的病理类型和复发率进行回顾性研究。结果228例成釉细胞瘤患者中有一般型成釉细胞瘤145例,单囊型成釉细胞瘤80例,周边型成釉细胞瘤3例;前两种病理类型患者平均就诊年龄(岁)分别为32.63±14.68和24.83±10.15,两者间有显著性差异(P<0.001);平均病程(月)分别为25.54±38.24和10.99±20.36,两者间有显著性差异(P<0.005)。一般型和单囊型成釉细胞瘤复发率分别为31.72%和15.00%,两者间有显著差异(P<0.01);在一般型成釉细胞瘤中丛状型和滤泡型两种主要亚型的复发率分别为17.65%和12.90%,两者间无显著差异(P>0.05)。结论单囊型成釉细胞瘤多见于青少年,发病年龄较一般型小,病程较一般型短,复发率比一般型低;而一般型中两种主要类型丛状型和滤泡型的复发率无明显差别。

Objective To investigate the clinicopathological features and recurrence rates of ameloblastomas between different types. Methods 145 eases of classic ameloblastomas and 80 cases of unicystic ameloblastomas among 228 cases of ameloblastomas were retrospectively analyzed on age, course, histologic type, recurrence rate. Results The average age （years） in classic type was 32. 63 ± 14. 68 , and 24. 83 ± 10. 15 in unicystic type, and it was found there was statistically significant difference between them （P 〈 0. 001 ）. The average course （months） in classic type was 25. 54 ±38. 24, and 10. 99 ±20. 36 in unicystic type, and significant statistical difference between them was also found （ P 〈 0. 005）. The recurrence rates of classic type and unieystie type were 31.72% and 15.00% respectively, with a significant difference in statistics （P 〈 0. 01 ）. However, among types of classic ameloblastoma, there was no significant statistical difference（ P 〉 0. 05 ） between follicular type with a recurrence rate of 17. 65%, and plexiform type with a recurrence rate of 12. 90%. Conclusion Unicystie ameloblastoma usually occurrs in younger people, with a shorter course than classic type. The recurrence rate of unicystic type ameloblastoma is lower than that of classic type. But there is no significant difference on recurrence rate between follicular type and plexiform type among classic type ameloblastoma.