6Niki Y,Yamada H,Kikuchi T,et al. Membrane associated IL-1 contributes to chronic synovitis and cartilage destruction in human IL-1 alphat tans genic mice[J]. J Immunol,2004,72(1):577-584.
7Dayer JM. Evidence for the biological modulation of IL-lactivity:the role of IL-1 Ra [J].Clin Exp Rheumato,2002,20(27):14-20.
8BR A M. Blocking the effects of IL-I in rheumatoid arthritis protects bone and cartilage[J].R heumatology, 2002,41(9):972-980.
9Matsuno H,Yudoh K,Katayama R,et al.The role of TNF-α in the pathogenesis of inflammation and joint destruction in rheumatoid arthritis(RA):a study using a human RA/SCD mouse chimera[J].Rheumatology:Oxford, 2002,41(3):329-337.
