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体外培养毛囊真皮鞘细胞与皮肤成纤维细胞形态结构和bFGF、EGFR表达差异 被引量：1

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摘要 Gharzi等初步证实毛囊真皮鞘细胞参与皮肤损伤修复，但相关作用机制研究报道不多。成纤维细胞是皮肤创伤愈合主要效应细胞，毛囊真皮鞘细胞与皮肤成纤维细胞一样均属于间充质细胞。本研究旨在通过两种细胞形态结构及部分愈合相关蛋白表达差异研究，初步探讨毛囊真皮细胞在创伤愈合中的作用。
作者 李幼忱 刘杰 王德文 左红艳 高亚兵 马俊杰
机构地区 军事医学科学院放射与辐射医学研究所
出处 《中华皮肤科杂志》 CAS CSCD 北大核心 2008年第10期693-695,共3页 Chinese Journal of Dermatology
基金 北京市自然科学基金（7042047）
关键词 皮肤成纤维细胞 毛囊真皮细胞 真皮鞘细胞 形态结构 表达差异 BFGF 体外培养 EGFR
分类号 R751 [医药卫生—皮肤病学与性病学]
  • 相关文献

参考文献5

  • 1Gharzi A, Reynolds A J, Jahoda CA. Plasticity of hair follicle dermal cells in wound healing and induction. Exp Dermatol, 2003, 12(2): 126-136.
  • 2李幼忱,刘杰,王德文,杨莉,高亚兵,马俊杰,马洪强,张康蓉.体外培养大鼠触须毛囊真皮鞘细胞的生物学特性及其超微结构[J].军事医学科学院院刊,2006,30(6):505-508. 被引量：2
  • 3Jahoda CA, Whitehouse J, Reynolds AJ, et al. Hair follicle dermal cells differentiate into adipogenie and osteogenie lineages. Exp Dermatol, 2003, 12(6): 849-859.
  • 4Hoogduijn MJ, Gorjup E, Genever PG. Comparative characterization of hair follicle dermal stem cells and bone marrow mesenchymal stem cells. Stem Cells Dev, 2006, 15( 1 ): 49-60.
  • 5Jahoda CA, Reynolds A J, Chaponnier C, et al. Smooth muscle alpha-actin is a marker for hair follicle dermis in vivo and in vitro. J Cell Sci, 1991, 99( Pt 3): 627-636.

二级参考文献10

  • 1Jahoda CA,Reynolds AJ.Hair follicle dermal sheath cells:unsung participants in wound healing[J].Lancet,2001,358(9291):1445-1448.
  • 2Richardson GD,Arnott EC,Whitehouse CJ,et al.Plasticity of rodent and human hair follicle dermal cells:implications for cell therapy and tissue engineering[J].J Invest Dermatol Symp Proc,2005,10 (3):180-183.
  • 3Jahoda CA,Reynolds AJ,Chaponnier C,et al.Smooth muscle alpha-actin is a marker for hair follicle dermis in vivo and in vitro[J].J Cell Sci,1991,99(Pt 3):627-636.
  • 4Ma DR,Yang EN,Lee ST.A review:the location,molecular characterization and multipotency of hair follicle epidermal stem cells[J].Ann Acad Med Singapore,2004,33(6):784-788.
  • 5Paus R,Cotsarelis G.The biology of hair follicles[J].N Eng1 J Med,1999,341(7):491-497.
  • 6Reynolds AJ,Lawrence C,Cserhalmi-Friedman PB,et al.Trans-gender induction of hair follicles[J].Nature,1999,402(6757):33-34.
  • 7Lako M,Armstrong L,Cairns PM,et al.Hair follicle dermal cells repopulate the mouse haematopoietic system[J].J Cell Sci,2002,115(Pt 20):3967-3974.
  • 8Jahoda CA,Whitehouse J,Reynolds AJ,et al.Hair follicle dermal cells differentiate into adipogenic and osteogenic lineages[J].Exp Dermatol,2003,12(6):849-859.
  • 9Katsuoka K,Schell H,Hornstein OP,et al.Comparative morphological and growth kinetics studies of human hair bulb papilla cells and root sheath fibroblasts in vitro[J].Arch Dermatol Res,1986,279 (1):20-25.
  • 10周春丽,叶庆佾,郝飞,刁庆春.分离酶法体外分离和培养人毛囊黑素细胞[J].中华皮肤科杂志,2001,34(5):389-390. 被引量：6

共引文献1

同被引文献10

  • 1李幼忱,刘杰,王德文,杨莉,高亚兵,马俊杰,马洪强,张康蓉.体外培养大鼠触须毛囊真皮鞘细胞的生物学特性及其超微结构[J].军事医学科学院院刊,2006,30(6):505-508. 被引量：2
  • 2Jahoda CA, Reynolds AJ. Hair follicle dermal sheath cells: unsung participants in wound healing [ J]. Lancet, 2001, 358 (9291) :1445 - 1448.
  • 3Gharzi A, Reynolds AJ, Jahoda CAB. Plasticity of hair follicle dermal ceils in wound healing and induction[ J]. Exp Dermatol, 2003, 12(2) :126 -136.
  • 4Reynolds A J, Lawrence C, Cserhalmi-Friedman PB, et al. Transgender induction of hair follicles [ J ]. Nature, 1999,402 ( 6757 ) : 33 - 34.
  • 5Lako M, Armstrong L, Cairns PM, et al. Hair follicle dermal cells repopulate the mouse haematopoietic system [ J ]. J Cell Sci, 2002, 115 ( Pt 20) :3967 - 3974.
  • 6Jahoda CA, Whitehouse J, Reynolds AJ, et al. Hair follicle dermal ceils differentiate into adipogenic and osteogenic lineages [ J ]. Exp Dermatol, 2003, 12(6) :849 -859.
  • 7Hoogduijn M J, Gorjup E, Genever PG. Comparative characterization of hair follicle dermal stem cells and bone marrow mesenchymal stem cells[J]. Stem Ceils Dev, 2006, 15( 1 ) : 49 -60.
  • 8Richardson GD, Arnott EC, Whitehouse CJ, et al. Plasticity of rodent and human hair follicle dermal cells: implications for cell therapy and tissue engineering [ J ]. J Invest Dermatol Symp Proc, 2005, 10(3): 180-183.
  • 9Gabbiani G. The myofibroblast in wound healing and fibrocontractive diseases[J]. J Pathol, 2003, 200(4) : 500 -503.
  • 10Jahoda CA, Reynolds AJ, Chaponnier C, et al. Smooth muscle alpha-actin is a marker for hair follicle dermis in vivo and in vitro [J]. J Cell Sei, 1991,99(Pt3) : 627 -636.

引证文献1

二级引证文献5

中华皮肤科杂志
2008年 第10期

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