轻度子宫内膜异位症腹腔液及血清中SOD LPO VitE的研究

Study on SOD.Lop and VitE levels in peritoneal fluid and plasma of patients with mild endometriosis.

将５１例经腹腔镜确诊的轻度子宫内膜异位症患者与２０例行腹腔镜绝育术的正常妇女的腹腔液及血清中的脂质过氧化物（ＬＰＯ）、超氧化物歧化酶（ＳＯＤ）、维生素Ｅ（ＶｉｔＥ）水平进行分析，结果表明：轻度子宫内膜异位症患者腹腔液中的ＬＰＯ明显高于正常对照组（Ｐ＜０．０１），腹腔液中的ＳＯＤ明显高低于正常对照组（Ｐ＜０．０１）。轻度内异症血清中的ＳＯＤ、ＬＰＯ与正常妇女比较无显著差异（Ｐ＞０．０５）。结论：这些变化考虑与局部异位的子宫内膜的病理变化有关，是导致不孕的重要因素之一。

Objective:To study the super oxide divergenase(SOD).Lipid per-oxidative(LPO) and VitE levels in peritoneal fluid(PF) as well as in plasma of the patients with mild eudometriosis.Design:The SOD.LPO and VitE levels in PF and plasma of 51 cases with mild endometriosis diagnosed by Laparoscopy were compared with those of 20 cases of normal women undergoing salpingoligation.Results:the LPO in PFof mild endometriosis patients was significantly higher(P<0.01) and the SOD was significantly Lower(P<001) than those of control group.The VitE concentration in PF and plasma of the patients was singnifcantly lower than that of control group(P<0.01).The SOD LPO levels in plasma had no difference (P>0.05)between the patients and the normal control.Conclusion:The PF changes is closely related to the local pathological change resulted from endometriosis and Local antioxide therapy would be valuable to the endometriosis. \ \