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罗格列酮钠联合培哚普利治疗初诊代谢综合征50例分析

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摘要 目的探讨罗格列酮钠联合培哚普利在初诊代谢综合征(MS)治疗中近期及远期疗效。方法按中华医学会糖尿病学分会代谢综合征防治建议诊断标准,选择含高血压、高血糖组分的初诊患者50例,应用罗格列酮钠联合培哚普利治疗6个月,随访空腹血糖、餐后2h血糖、糖化血红蛋白、血压、体重指数。结果血糖、血压恢复正常患者情况:治疗6个月后占84%(42/50),停药6个月后占76%(38/50),停药1年后占68%(34/50),漏服药次数小于2%。结论肥胖及胰岛素抵抗与MS的发病率密切相关,改善胰岛素的敏感性是MS的根本治疗措施。罗格列酮钠联合培哚普利治疗MS依从性好,近期及远期疗效好,值得推荐为初诊的初始治疗方案。
作者 吕德纯
出处 《重庆医学》 CAS CSCD 2008年第19期2234-2235,共2页 Chongqing medicine
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