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实验性癫痫动物模型的研究进展 被引量：4

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作者 付林 傅峻峰 陈启雄
机构地区 重庆医科大学附属儿童医院新生儿科
出处 《重庆医学》 CAS CSCD 2008年第19期2237-2239,共3页 Chongqing medicine
基金 重庆医科大学博士启动基金资助项目(0200101060)
关键词 癫痫 动物模型 大发作 失神发作 部分性发作
分类号 R742.1 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献14

  • 1Jefferys JGR. Models and mechanisms of experimental epilepsies[J]. Epilepsia, 2003,44 (12) : 44.
  • 2Holmes GL. Animal model studies application to human patients[J]. Neurology,2007,69(24) : 28.
  • 3Edward DF, Staley KJ, Sutula TP. The search for animal models of epileptogenesis and pharmacoresistance: are there biologic barriers to simple validation strategies[J]. Epilepsia, 2002,43 (11) :1275.
  • 4Pitknen A, McIntosh TK. Animal models of post-traumatic epilepsy[J]. Neurotrauma,2006,23(2):241.
  • 5White HS. Preclinical development of antiepileptic drugs: past, present, and future directions [J]. Epilepsia, 2003,44 (7):2.
  • 6Jefferys JGR. Models and mechanisms of experimental epilepsies[J]. Epilepsia,2003,44(12) :44.
  • 7Kondziella D, Hammer J, Sletvold O, et al. The pentylenetetrazole-kindling model of epilepsy in SAMP8 mice: glial-neuronal metabolic interactions[J]. Neuroehem Int, 2003,43 (7) : 629.
  • 8Wang Y, Zhou D, Wang B, et al. A kindling model of pharmacoresistant temporal lobe epilepsy in Sprague-Dawley rats induced by Coriaria lactone and its possible mechanism. [J] Epilepsia,2003 ,44(4) :475.
  • 9Wu J, Ellsworth K, Ellsworth M, et al. Abnormal benzodiazepine and zinc modulation of GABAA receptors in an acquired absence epilepsy model[J]. Brain Res,2004,1013 (2) : 230.
  • 10Ostojic ZS, Ruzdijic S, Car M, et al. The connection between absence-like seizures and hypothermia induced by penicillin:possible implication on other animal models of peril mal epitepsy[J]. Brain research, 1997,777 : 86.

同被引文献50

  • 1徐向平,汪天柱.癫痫患儿与实验性癫痫动物生长抑素的测定及意义[J].中华儿科杂志,1996,34(4):264-266. 被引量：5
  • 2陈刚,邓艳春,王小木,尚学义.癫痫大鼠海马神经元和星形胶质细胞的病理演变[J].中华神经外科疾病研究杂志,2007,6(3):229-232. 被引量：8
  • 3郑乃智,阮旭中,李震中,王群.青霉素、戊四氮、美解眠癫痫模型的比较[J].临床脑电学杂志,1997,6(2):101-102. 被引量：27
  • 4黄绍平,李丹,张婕.癫痫持续状态后大鼠大脑中P糖蛋白的表达及其年龄特征[J].中华儿科杂志,2007,45(8):628-630. 被引量：2
  • 5Shibley H,Smith BN.Pilocarpine-induced status epilepticus results in mossy fiber sprouting and spontaneous seizures in C57BL/6 and CD-1 mice[J].Epilepsy Res,2002,49(2):109-120.
  • 6Mac Corkle RA,Tan TH.Mitogen-activated protein kinases in cell-cycle control[J].Cell Biochem Biophys,2005,43(3):451-461.
  • 7Liu AL,Wang XW,Liu AH,et al.JNK and p38 were involved in hypoxia and reoxygenation-induced apoptosis of cultured rat cerebellar granule neurons[J].Exp Toxicol Pathol,2009,61(2):137-143.
  • 8Yang Y,Zhu X,Chen Y,et al.p38 and JNK MAPK,but not ERK1/2 MAPK,play important role in colchicine-induced cortical neurons apoptosis[J].Eur J Pharmacol,2007,576(1/3):26-33.
  • 9Che Y,Yu YM,Han PL,et al.Delayed induction of p38 MAPKs in reactive astrocytes in the brain of mice after KA-induced seizure[J].Brain Res Mol Brain Res,2001,94(1/2):157-165.
  • 10Kim SW,Yu YM,Piao CS,et al.Inhibition of delayed induction of p38 mitogen-activated protein kinase attenuates kainic acid-induced neuronal loss in the hippocampus[J].Brain Res,2004,1007(1/2):188-191.

引证文献4

二级引证文献5

重庆医学
2008年 第19期

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