小刺猴头子实体多糖治疗萎缩性胃炎的实验研究

Experimental Study on Hericium caput-medusae(Bull.exFr) Pers.Polysaccharide in Treatment of Chronic Atrophic Gastritis

目的观察小刺猴头子实体多糖对慢性萎缩性胃炎的影响。方法采用主动免疫加胆汁、热水灌胃的综合方法模型,醋酸扭体法。结果胃蛋白酶活性升高,胃游离酸显著升高;改善胃黏膜的萎缩,对胃黏膜的炎症也有抑制作用。结论小刺猴头子实体多糖具有治疗慢性萎缩性胃炎的作用。

Objective To study thc protective and therapeutic effects ofttericium caput-medusae （Bull.exFr） Pets on atrophic gastritis in rats. Msthods The model was established by methods of active immunity and gastrogavagc with bile and hot water. Results The hydrochloric acid of gastritis juice was significantly increased with the difference being significant. Pepsin activity rose. Epithelial cel- lular morphosis and atrophic degree of gastro mucosal gland were obviously improved. Inflammation cells were reduced significantly. Conclusion Hericiura caput-medusae （Bull.exFr） Pets. Polysaccharide had remarkably preventive and therapeutic effects on atrophic gastritis of rats.