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肝脏星状细胞与免疫系统 被引量:1

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摘要 肝星状细胞(hepatic stellate cells)是一种非实质性肝细胞,分布于Disse间隙.占肝非实质细胞总数的5%~10%。其有静止和活化两种表型.正常情况下呈静止状态.主要参与维生素A代谢.其胞浆中含有类视黄醇物质的脂滴,贮存体内80%的维生素A.并通过自身的收缩调节血管和肝窦血流;肝脏损伤时,其被激活表现出细胞因子的增殖和分泌、基质金属蛋白酶及其抑制物的产生、大量细胞外基质(extracellular matrix,ECM)的合成等功能。
出处 《外科理论与实践》 2008年第5期473-476,共4页 Journal of Surgery Concepts & Practice
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