培福新治疗创伤后伤口感染57例疗效观察

Curative Observation of Pefloxacin Treating Wound Infection in 57 Cases

用培福新（ｐｅｆｌｏｘａｃｉｎ）治疗创伤后伤口感染５７例，并设青霉素素、头孢菌素类或氨基糖甙类两种联合应用为对照组进行对比分析．结果表明，治疗组脓液消退后伤口愈合时间显著少于对照组（Ｐ＜０．０５），其治疗有效率为１００％，显著高于对照组．认为该药具有耐药率低、生物利用度高、组织渗透力强、疗效好的特点，其常规剂量就可有效控制创伤后伤口化脓性感染，包括深部软组织重度感染．

Pefloxacin was used to cure wound infection in 57 cases, which were analytically contrasted with a control group treated by penicillins, cephalosporins or aminoglycosides. As shown in the result, the wound healing time after the disappearance of pus was obviously less (P<0.05) in the cured than in the contrasted; and the curative rate was 100% , a figure significantly higher than that of the latter. It was thought that the drug has such advantages as low drug resistance, high bioavailability, strong tissue osmolarity and good effect. Its routine dosage can effectively control purutent wound infection, including the severe infection of soft tissue at the deep layer.