无创脑水肿动态监测在自发性脑出血患者中的应用

Cerebral Edema Monitoring by Non-invasive and Dynamical Method in Patients With Spontaneous Intracerebral Hemorrhage

目的:观察自发性脑出血(SICH)患者甘露醇治疗前后脑水肿的动态演变。方法:选择30例SICH患者在甘露醇治疗前、后不同时点运用无创脑水肿动态监护仪动态检测扰动系数。结果:治疗后30 min、1 h、3 h脑出血侧和对侧分别与治疗前比较,有显著性差异(P<0.01);在治疗5 d脑出血侧与对侧相比,有显著性差异(P<0.01),第7天无差异;SICH患者出血侧在治疗后第7天与治疗前比较有显著性差异(P<0.01)。结论:甘露醇治疗3 h后SICH患者全脑脑水肿减轻,脑出血侧脑水肿在用药后5 d内一直重于对侧,第7天出血侧脑水肿减轻。

Objective： To observe the dynamical changes of cerebral edema caused by spontaneous intracerebral hemorrhage（SICH）.Methods： Thirty patients with SICH were recruited for this study.The change of agitating coefficient in the 30 patients was dyamically detected by non-invasive brain edema monitor before and after mannitol infusion at different time points.Results： The study displayed that the difference in agitating coefficient in SICH side and unaffected side was significant before and after mannitol infusion（30min,1 h and 3 h,P〈0.01）.Conclusion： Brain edema of SICH will be alleveated 3 hours after mannitol infusion.Brain edema in SICH side was more serious than that in unaffected side for a few days and will be relieved on day 7.