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Survivin基因与喉鳞状细胞癌

Survivin Gene and Laryngeal Squamous Cell Carcinoma
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作者 李磊 马士崟
机构地区 蚌埠医学院 蚌埠医学院第一附属医院耳鼻咽喉-头颈外科
出处 《解剖与临床》 2008年第5期379-381,共3页 Anatomy and Clinics
关键词 喉鳞状细胞癌 SURVIVIN基因 肿瘤细胞 细胞凋亡 凋亡抑制基因 细胞增殖 凋亡机制 肿瘤治疗
分类号 R739.65 [医药卫生—肿瘤] R735.2 [医药卫生—肿瘤]
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参考文献26

  • 1[1]Jaattela M.Escaping cell death:survival proteins in cancer.Exp Cell Res,1999,248(1):30～43
  • 2[2]Konno R,Yamakawa H,Utsunomiya H,et al.Expression of survivin and bcl-2 in the normal human endometrium J.Mol Hum Reprod,2000,6(6):529～534
  • 3[3]Ambrosini G,Adida C,Altieri DC.A novel anti-apoptosisi gene,survivin,expressed in cancer and lymphoma.Nat Med,1997,3(8):917～921
  • 4[4]Mahotka C,Wenzel M,Springer E,et al.Survivin-deltaEx3 and surviving-2B:two novel splice variants of the apoptosis inhibitor surviving with different antiapoptotic properties.Cancer Res,1999,59(24):6097～6102
  • 5[5]Badran A,Yoshida A,Ishikawa K,et al.Identification of a novel splice variant of the human antiapoptopsis gene survivin.Biochem Biophys Res Commun,2004,314(3):902～907
  • 6[6]Caldas H,Honsey LE,Altura RA.Survivin2-α:a novel Survivin splice variant expressed in human malignancies.Mol Cancer,2005,4(1):1～11
  • 7[7]Fortugno P,Wall NR,Giodini A,et al.Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function.Cell Sci,2002,115(Pt3):575～585
  • 8[8]O'Connor DS,Grossman D,Plescia J,et al.Regulation of apoptosis at cell division by p34cdc2 phosphorylation of surviving.Proc Natl Acad Sci USA,2000,97(24):13103～13107
  • 9[9]Shin S,Sung B J,Cho Y S,et al.An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and-7.Biochemistry,2001,40(4):1117～1123
  • 10[10]Du C,Fang M,Li Y,et al.Smac,a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition.Cell,2000,102(1):33～42

二级参考文献11

  • 1任重 王琰 等.p16抑癌基因在喉癌中的表达及其与癌恶性度和颈淋巴结转移的关系[J].中华耳鼻咽喉科杂志,1997,32(1):51-51.
  • 2Ambrosini G, Adida C,Altieri DC,et al. A novel anti-apoptosis gene,survivin,expressed in cancer and lymphoma. Nat Med,1997,3: 917-921.
  • 3Iamm I, Wang Y, Sausville E,et al. IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas(CD95), Bax, caspases,and anticancer drugs. Cancer Res,1998,58:5315-5320.
  • 4Shin S, Sung BJ, Cho YS, et al. An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and caspase-7. Biochemistry,2001,40:1117-1123.
  • 5Suzuki A, Hayashida M, Ito T, et al. Survivin initiates cell cycle entry by the competitive interaction with Cdk4/p16INK4a and Cdk2/cyclin E complex activation. Oncogene,2000,19:3225-3234.
  • 6Dong Y, Sui L, Watanabe Y, et al. Survivinn expression in laryngeal squamous cell carcinomas and its prognostic implications. Anticancer Res,2002,22:2377-2384.
  • 7Kawasaki H, Toyoda M, Shinohara H, et al. Expression of survivin correlates with apoptosis proliferation, and angiogenesis during human colorectal tumorigenesis. Cancer,2001,91:2026-2032.
  • 8Stone S, Dayananth P, Jiang P, et al. Genomic structure,expression and mutational analysis of the p15(MTS2)gene. Oncogene,1995,11:987-991.
  • 9李建忠,杨劲松,易自翔,林有辉,周爱东.喉癌和喉乳头状瘤组织中人乳头状瘤病毒和p16蛋白的检测[J].中华耳鼻咽喉科杂志,2001,36(1):51-54. 被引量：11
  • 10李福才,康宁,李英慧,贺光,林长坤,孙兴和,高宏明,孙开来.喉癌p16、p15基因纯合性缺失的研究[J].中华医学遗传学杂志,2002,19(1):30-32. 被引量：3

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解剖与临床
2008年 第5期

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