睡眠障碍伴便秘患者胃肌电活动的临床观察

The clinical observation on gastric myoelecerical activity of the patients with sleep disorder and constipation

目的观察睡眠障碍伴便秘患者胃肌电活动的特点,为临床治疗提供理论依据。方法采用匹斯堡睡眠指数量表,对同期连续就诊的睡眠障碍伴便秘患者及睡眠障碍不伴便秘患者进行睡眠质量测评,同时设立健康志愿者作为对照。采用多导睡眠仪和胃电图记录仪对上述试验者进行整晚同步监测,在对不同试验组睡眠指数进行对比分析的基础上,重点观察其睡眠期的浅睡眠S2期、深睡眠S4期的胃肌电主频变化情况。结果睡眠障碍伴便秘患者的匹斯堡睡眠指数显著高于无便秘患者;便秘患者在S2、S4、REM期胃电主频较正常对照组明显下降。从觉醒至浅睡眠再到深睡眠胃电主频逐渐降低。便秘患者在REM睡眠期胃电主频升高幅度较正常对照组小。结论睡眠障碍伴有便秘患者存在显著胃电活动障碍。

Objective To detective the character of the gastric myoelecerical activity in patients with sleep disorder and constipation, for proving the evidence on clinical therapeutics. Methods In the test, we selected some patients： 12 patients with sleep disorder and constipation, 10 patients only with sleep disorder and 6 normal volunteers. All subjects were respectively tested by PSQI, slept one night in the sleep laboratory and underwent polysomngraphic monitoring to determine sleep patterns, and recording of the EGG from surface electrodes. Results The patients with sleep disorder and constipation was significantly higher PSQI, the patients with sleep disorder and constipation was significantly lower dominant frequency. There was a decrease in the dominant frequency from waking to S2, and from S2 to S4 sleep, and a subsequent increase from S4 to REM sleep. The patients with sleep disorder and constipation had a smaller increase in the DF with normal volunteers in REM sleep. Conclusion Patients with sleep disorder and constipation have significant disorder in gastric myoelecerical activity.